SMGM: Bruce Yanker, Ph.D. Professor of Genetics and Neurology at Harvard Medical School

BWH DIVISION OF GENETICS

2025-2026 Academic year Seminars in Molecular and Genomic Medicine (SMGM)

Tuesday, 3:00 PM – 4:00 PM • NRB 457

SMGM: Bruce Yanker, Ph.D. Professor of Genetics and Neurology at Harvard Medical School

“Metallo-Genomic Regulation in Aging and Neurodegeneration”

Bruce A. Yankner, M.D., Ph.D. is Professor of Genetics and Neurology at Harvard Medical School, Co-Director of the Paul F. Glenn Center for the Biology of Aging, Co-Chair of the Harvard Initiative on Aging, and Director of the Harvard Neurodegeneration Training Program. Dr. Yankner graduated from Princeton University, received his M.D. and Ph.D. from Stanford University, and did a residency at Massachusetts General Hospital. His work has advanced our understanding of pathogenic mechanisms in Alzheimer’s disease, Parkinson’s disease, Down’s syndrome, and diabetes, beginning with the discovery that amyloid proteins are toxic molecules. His laboratory was also the first to describe the transcriptome of the aging human brain, its evolution, and a role for DNA damage in gene regulation during aging.  More recently, his laboratory has identified a pathway of gene regulation that modulates aging, memory loss, and the pathology of Alzheimer’s disease.