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Special Seminar Dr. Gen-Sheng Feng
Special Seminar Dr. Gen-Sheng Feng, Thursday, June 5th, 2025, at 9 AM in NRB Room 457.
Talk Title: “Mechanism and Immunotherapy of Liver Cancer”
Topic: Mechanisms of liver tumorigenesis, challenges and opportunities in cancer immunotherapy.
Location: New Research Building (NRB), Room 457, 9:00 AM
Bio: Gen-Sheng Feng, PhD, is a Professor in the Departments of Pathology and Molecular Biology at the University of California, San Diego. His research investigates the molecular and cellular mechanisms underlying liver cancer, with a particular focus on paradoxical roles of classical oncoproteins and the immune microenvironment in hepatocarcinogenesis.
Dr. Feng’s laboratory has made foundational discoveries in liver cancer biology, including the unexpected tumor-suppressive roles of signaling molecules traditionally viewed as oncogenic. His group has demonstrated that loss of such molecules in hepatocytes can paradoxically exacerbate tumor development, reshaping our understanding of liver tumor initiation. More recently, his team has pioneered combinatorial immunotherapy strategies that synergize innate and adaptive immune activation to prevent and treat liver cancer, revealing key liver-specific barriers to checkpoint blockade efficacy.
A prolific and highly cited investigator, Dr. Feng has authored over 180 peer-reviewed publications. His research has been continuously funded by the NIH since 1996. Dr. Feng is an elected Fellow of the American Association for the Advancement of Science and serves on the editorial boards of Hepatology, Journal of Hepatology, and Molecular Cancer Research, among others.
Please contact organizing Administrator Alisha Samuel amsamuel@mgb.orgwith any questions or to arrange 1:1 meetings with the speaker (a few slots remaining)